Stem Cells
The University has a major activity in the derivation, reprogramming and controlled differentiation of stem cells. Funded through initiatives and fellowships launched by the BBSRC and MRC, the University is enhancing the basic science foundation that underpins the development of stem cell therapies.
Stem cells can be induced to differentiate into a variety of cell types in vitro. At Nottingham, we study human, mouse and farm animal embryonic stem cells, mesenchymal cells, haematopoeitic stem cells, fetal liver stem cells and gut stem cells.
Our programmes aim to link basic scientific and technological advances with clinical expertise to translate our research into new patient treatments. The promise of stem cells for transplantation studies could provide revolutionary new regenerative medicine opportunities.
We also use stem cells in culture to model human diseases and uncover the mechanisms of disease processes, including cancer, digestive diseases, lung disorders, heart disease, muscular dystrophies and blood disorders.
Our interests extend to using human stem cells to test new drugs, minimising the use of animals such as mice and providing more relevant human cells for testing.
Expertise at Nottingham:
- Dr Lorraine Young, School of Human Development
- Professor Keith Campbell, School of Biosciences
- Dr Rhodri Jones, School of Molecular Medical Sciences
- Dr Chris Denning, School of Biology
- Professor Ian Hall, School of Medical & Surgical Sciences
- Professor Yash Mahida, School of Medical & Surgical Sciences
- Professor Sue Watson, School of Medical & Surgical Sciences
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